Thanks Peter...that actually seems the most probable answer. Thanks also to all who responded.

Looks like Sant'Anna is in Tuscany. One thing Gramps was adamant about was that he was a Neopolitan.

Legend has it that the spelling of his name changed significantly, so I have not been able to find him on the Ellis Island website, by the way can someone translate Lucap's response ?

Thanks to everyone who responded.

My grandfather (the only Italian in my ancestry) told everyone he was from a town in the area of Naples called Sandan. We all took him at his word. He passed away decades ago. Now, in searching my family roots, I find that there appears to be no such town.

Is there an area or town near Naples that ...